COVID mRNA vaccines create 'numerous off-target products' that get stuck in heart cells: study
Federal regulators are caught between old-guard conservatives who demand continued mRNA funding, Rep. Massie's demand to "immediately revoke licensure of the mRNA COVID shots" for "shoddy" approvals and side effects.
When Health and Human Services Secretary Robert F. Kennedy Jr. shifted nearly $500 million designated for mRNA vaccine development to "safer, broader vaccine platforms that remain effective even as viruses mutate," predictable wailing followed from the public health establishment and mainstream media but also some old-guard conservatives.
National Review editors praised COVID-19 vaccines for their belatedly alleged protections against severe outcomes, citing President Biden's Centers for Disease Control and Prevention for the claim they reduced hospitalization and death by 70% among those vaccinated, even as the editors acknowledged the virus naturally became "less severe over time."
The publication's intern even called COVID vaccines, whose inability to stop infection and transmission was known to then-CDC Director Rochelle Walensky a month after emergency use authorization, "the most phenomenal medical breakthrough of the 21st century."
Yet peer-reviewed global research keeps identifying severe adverse events following mRNA vaccination in some groups at low risk from COVID, and a German-led paper in the official journal of the International Union of Immunological Societies offers a causal explanation.
"Our findings reveal that numerous off-target products are produced by mRNA-based corona vaccines following translation of the encoded spike monomers," said researchers affiliated with institutes on physiology, medical informatics, pharmacology and "Molecular and Translational Therapeutic Strategies" in Germany and Hungary.
"These off-target products may be responsible for both acute vaccination reactions and long-term side effects," says their Frontiers in Immunology abstract for the paper, accepted July 22, whose "final, formatted version" will be published "soon."
The research is making small waves on X in several languages. "BOMBSHELL STUDY," proclaimed Utah doctor Kirk Moore, who faced 35 years in prison on charges of throwing away COVID vaccine doses and distributing fraudulent vaccination record cards.
Attorney General Pam Bondi dropped Moore's case, initiated by the Biden administration, shortly after the trial started last month, preempting his jury-nullification plan to obtain hidden records allegedly showing the neat overlap between COVID vaccination and deaths.
Kennedy's mRNA funding redirect is the "first real policy course correction in a vaccine ecosystem that had drifted from science into speculative biotech fantasy," said former Ecohealth Alliance Vice President Andrew Huff, whose nonprofit passed U.S. taxpayer money to the Wuhan Institute of Virology and claims the lab "developed" SARS-CoV-2.
Huff laid out several recommendations for what should replace the mRNA pursuit, namely vaccine development that induces "broad, long-lasting immunity" across virus families and stops transition "at the point of entry – especially the respiratory mucosa."
'Sticky spike clumps' following vaccination 'trapped inside' heart cells
The Frontiers paper follows preprint research, not yet peer-reviewed, by top advisers to President Trump's CDC and Food and Drug Administration that found higher-than-expected pregnancy losses following early mRNA vaccination based on analysis of Israeli medical records three years before and after SARS-CoV-2 emerged in China.
Published last month in the peer-reviewed journal Cancers, Japanese researchers also found as little as two mRNA primary shots and a booster "associated with poorer overall survival" in patients with pancreatic cancer, after probing why survival rates in their hospital fell in 2022 and 2023 after years of steady increases.
Before joining the Trump administration, FDA Commissioner Marty Makary and his recently departed top vaccine regulator, Vinay Prasad, coauthored a Journal of Medical Ethics paper that estimated for every one hospitalization prevented by COVID boosters in "previously uninfected" 18-29 year-olds, 18-98 of them will suffer serious adverse events.
Typical of COVID vaccine-related research that makes it through peer review, the Frontiers paper assumes "mRNA-based vaccines have proven highly effective in reducing severe disease and mortality" and post-vaccination heart inflammation is "rare."
But because "recent longitudinal studies have raised questions regarding [heart inflammation's] long-term impact," the German and Hungarian researchers sought to understand "the molecular mechanisms potentially involved in vaccine-associated cardiac side effects."
TrialSiteNews translated the paper's explanation of how Pfizer and Moderna mRNA vaccines work – prompting cells to produce two versions of the spike protein monomer – and what went wrong, with furin enzymes "reliably" chopping monomers into "S1 subunits" but producing inconsistent numbers of S2 subunits depending on cell and vaccine.
Just a few hours after vaccination, "the spike proteins began clumping together into large, sticky aggregates" that "formed in consistent patterns unique to each type of cell tested," and in heart cells, those clusters "slowed down cell growth, triggered oxidative stress, and kicked off an inflammatory response," TrialSiteNews said.
"Only the secreted S1 subunit was detected as an immunogen in the supernatant of all three cell lines," the Frontiers paper said. "Everything else—including the sticky spike clumps – stayed trapped inside, raising new questions about what the body is really doing with these spike proteins after vaccination," also according to TrialSiteNews.
Massie: 'FDA should immediately revoke licensure'
Boosters of COVID vaccine are touting other new research that purportedly proves "mRNA vaccines are incredibly safe": a Danish study published last month in a Journal of the American Medical Association publication that evaluated a new vaccine formulation in elderly people who had already taken three jabs, without an unvaccinated control group.
The researchers counted only severe adverse events within 28 days, excluded SAEs from 28-42 days as a "buffer period" and counted SAEs 43 or more days later as not receiving the JN.1 variant formulation. They still found an association with myocarditis from the JN.1 jab, with an upper confidence boundary interval of three times greater risk.
The mainstream media are also touting a 23-year Danish study published in the Annals of Internal Medicine last month that found no connection between "aluminum-adsorbed vaccines" in early childhood and "autoimmune, atopic or allergic, and neurodevelopmental disorders" such as autism, rebutting Kennedy's criticisms of its methodology
Some skeptics of the autism-vaccine theory found fault with the study too, noting the Danish childhood schedule is less bloated than the American schedule so Danish children likely consumed less aluminum, the study is missing negative controls intended to detect confounding and bias and the researchers made voluminous choices on whom to include and exclude.
The dueling research comes as Kennedy's HHS throws bones to vaccine skeptics upset with his FDA's approval of Moderna's latest mRNA vaccine, albeit only recommended for people 65 and up and 12-64 with higher risk from underlying medical conditions, then approving its old vaccine for children 6 months through 11 years at increased COVID risk.
The FDA said it won't approve annual COVID boosters for healthy people under 65 without clinical trials, and Kennedy approved the reconstituted Advisory Committee on Immunization Practices' removal of mercury-based thimerosal from flu vaccines, which still lingers in some multi-dose shots 24 years after it was largely phased out of childhood vaccines.
That's not good enough for critics such as Kentucky GOP Rep. Thomas Massie, who on Thursday said, "The FDA should immediately revoke licensure of the mRNA COVID shots" due to a "shoddy approval process and known side effects."
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- shifted nearly $500 million designated
- predictable wailing followed from the public health establishment
- mainstream media
- National Review editors praised COVID-19 vaccines
- The publication's intern
- Rochelle Walensky a month after emergency use authorization
- Frontiers in Immunology abstract for the paper, accepted July 22
- small waves on X
- "BOMBSHELL STUDY," proclaimed Utah doctor Kirk Moore
- Attorney General Pam Bondi dropped Moore's case
- jury-nullification plan to obtain hidden records
- nonprofit passed U.S. taxpayer money to the Wuhan Institute of Virology
- lab "developed" SARS-CoV-2
- Huff laid out several recommendations
- higher-than-expected pregnancy losses following early mRNA vaccination
- two mRNA primary shots and a booster "associated with poorer overall survival"
- recently departed top vaccine regulator Vinay Prasad
- Journal of Medical Ethics paper
- TrialSiteNews
- "mRNA vaccines are incredibly safe"
- Journal of the American Medical Association publication
- elderly people who had already taken three jabs
- counted severe adverse events within 28 days
- association with myocarditis
- mainstream media are also touting
- Annals of Internal Medicine
- rebutting Kennedy's criticisms
- Danish childhood schedule is less bloated
- study is missing negative controls
- detect confounding and bias
- researchers made voluminous choices
- FDA's approval of Moderna's latest mRNA vaccine
- approving its old vaccine for children 6 months through 11 years
- won't approve annual COVID boosters for healthy people
- removal of mercury-based thimerosal from flu vaccines
- Thomas Massie, who said Thursday