'TODAY' show co-anchor Savannah Guthrie's mother reported missing, homicide detectives at scene

NBC's "TODAY" show co-anchor Savannah Guthrie's mother was reported missing in Arizona, with homicide detectives called out to process the scene.

Guthrie's mother, Nancy Guthrie, 84, was last seen Saturday night in her home outside Tucson, according to a missing persons flyer, NBC News reported. Her family reported her missing around noon Sunday, Pima County Sheriff Chris Nanos said.

Nanos said that aspects of the scene at the home caused "grave concern."

"This one stood out because of what was described to us at the scene and what we found and located just in looking at the scene," he said, without elaborating.

Nanos said that homicide detectives were called out to process the scene, which is not standard protocol, and foul play cannot be ruled out.

"TODAY" show co-host Jenna Bush Hager reported on-air that Nancy Guthrie needs to take daily medication to survive.

U.S. Customs and Border Protection is assisting, and the FBI is aware of the case.

Guthrie said in a statement on Monday, “[O]n behalf of our family, I want to thank everyone for the thoughts, prayers, and messages of support.”

"Right now, our focus remains on the safe return of our dear mom. We thank law enforcement for their hard work on this case and encourage anyone with information to contact the Pima County Sheriff’s Department at: 520-351-4900."

Nancy Guthrie's family last saw her at home around 9:30 p.m. to 9:45 p.m. Saturday, Nanos said.

"Miss Guthrie is 84 years old and is not in good physical health," he said. He added that her family reported that she had no cognitive issues.

The sheriff said that drones, an airplane, a helicopter, volunteers, and search-and-rescue dogs loaned from CBP were all scouring the area for Nancy Guthrie.